Boase D L, Gale R E, Huehns E R
Br J Ophthalmol. 1980 Oct;64(10):745-50. doi: 10.1136/bjo.64.10.745.
The oxyhaemoglobin dissociation curve (ODC) was investigated in 15 patients with Eales's disease and 11 controls to test the hypothesis that Eales's disease is caused by retinal hypoxia secondary to impaired oxygen release from the blood. Patients with the peripheral form of Eales's disease did not have any significant difference in the P50 values when compared with the controls. However, the P50 values were significantly lower (P < 0.005) for the patients with mixed retinopathy. This degree of increased oxygen affinity is not physiologically significant but may reflect an intrinsic abnormality of the red cells in these cases.
对15例伊尔斯病患者和11名对照者的氧合血红蛋白解离曲线（ODC）进行了研究，以检验伊尔斯病是由血液中氧释放受损继发的视网膜缺氧所致这一假说。外周型伊尔斯病患者与对照者相比，其P50值无显著差异。然而，混合性视网膜病变患者的P50值显著更低（P < 0.005）。这种氧亲和力增加的程度在生理上并不显著，但可能反映了这些病例中红细胞的内在异常。
