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[硝基蓝四唑试验——综述]

[The NBT test--a review].

作者信息

John M

出版信息

Folia Haematol Int Mag Klin Morphol Blutforsch. 1980;107(3):358-71.

PMID:6159274
Abstract

The NBT-test is a technique particularly used in its stimulated variant for testing granulocyte metabolism and in this capacity it is an integrated part of the test programme for differentiating neutrophilic dysfunctions. Its sphere of application is the diagnosis of progressive septic granulomatosis. The variety of the methods used makes it difficult to compare the results described by the various authors. Therefore, standardization is urgently necessary. A differentiation of bacterial and non-bacterial infections as well as of other febrile diseases is not possible with the unstimulated test. Investigations of the longitudinal section, however, allow the activity of the disease to be evaluated (with initially high numbers of granulocytes being positive in the nitroblue tetrazolium test).

摘要

硝基蓝四氮唑试验(NBT试验)是一种特别用于其刺激变体以检测粒细胞代谢的技术,并且在此方面它是区分嗜中性粒细胞功能障碍检测程序的一个组成部分。其应用领域是进行性脓毒性肉芽肿病的诊断。所使用方法的多样性使得难以比较不同作者所描述的结果。因此,迫切需要进行标准化。未刺激的试验无法区分细菌感染和非细菌感染以及其他发热性疾病。然而,对纵向切片的研究可以评估疾病的活动情况(最初在硝基蓝四氮唑试验中粒细胞阳性数量较高)。

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