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Inhibition of sulfate conjugation of N-hydroxy-2-acetylaminofluorene in isolated perfused rat liver and in the rat in vivo by pentachlorophenol and low sulfate.

作者信息

Meerman J H, van Doorn A B, Mulder G J

出版信息

Cancer Res. 1980 Oct;40(10):3772-9.

PMID:6159969
Abstract
摘要

相似文献

1
Inhibition of sulfate conjugation of N-hydroxy-2-acetylaminofluorene in isolated perfused rat liver and in the rat in vivo by pentachlorophenol and low sulfate.五氯苯酚和低硫酸盐对离体灌注大鼠肝脏及大鼠体内N-羟基-2-乙酰氨基芴硫酸结合反应的抑制作用
Cancer Res. 1980 Oct;40(10):3772-9.
2
Role of sulfation in the formation of DNA adducts from N-hydroxy-2-acetylaminofluorene in rat liver in vivo. Inhibition of N-acetylated aminofluorene adduct formation by pentachlorophenol.硫酸化在大鼠肝脏中N-羟基-2-乙酰氨基芴体内形成DNA加合物中的作用。五氯苯酚对N-乙酰化氨基芴加合物形成的抑制作用。
Carcinogenesis. 1981;2(5):413-6. doi: 10.1093/carcin/2.5.413.
3
Prevention of the hepatotoxic action of N-hydroxy-2-acetylaminofluorene in the rat by inhibition of N-O-sulfation by pentachlorophenol.通过五氯苯酚抑制N-O-硫酸化作用预防大鼠体内N-羟基-2-乙酰氨基芴的肝毒性作用。
Life Sci. 1981 May 21;28(21):2361-5. doi: 10.1016/0024-3205(81)90501-4.
4
Sulfation in the metabolism and mutagenicity of N-hydroxy-2-fluorenylacetamide.N-羟基-2-芴基乙酰胺代谢及致突变性中的硫酸化作用。
Natl Cancer Inst Monogr. 1981 Dec(58):113-6.
5
The initiation of gamma-glutamyltranspeptidase positive foci in the rat liver by N-hydroxy-2-acetylaminofluorene. The effect of the sulfation inhibitor pentachlorophenol.
Carcinogenesis. 1985 Jun;6(6):893-7. doi: 10.1093/carcin/6.6.893.
6
Autoradiographic studies on in vivo covalent binding of N-hydroxy-2-acetylaminofluorene in rat liver containing gamma-glutamyltranspeptidase-positive foci. The effect of the sulfation-inhibitor pentachlorophenol.
Carcinogenesis. 1987 Apr;8(4):571-5. doi: 10.1093/carcin/8.4.571.
7
Persistence of DNA adducts in rat liver and kidney after multiple doses of the carcinogen N-hydroxy-2-acetylaminofluorene.多次给予致癌物N-羟基-2-乙酰氨基芴后大鼠肝脏和肾脏中DNA加合物的持续性。
Cancer Res. 1982 Apr;42(4):1348-54.
8
Effect of glutathione depletion on the hepatotoxicity and covalent binding rat liver macromolecules of N-hydroxy-2-acetylaminofluorene.谷胱甘肽耗竭对N-羟基-2-乙酰氨基芴的肝毒性及与大鼠肝脏大分子共价结合的影响。
Cancer Res. 1985 Mar;45(3):1132-9.
9
The role of sulfation in the metabolic activation of N-hydroxy-4'-fluoro-4-acetylaminobiphenyl.硫酸化在N-羟基-4'-氟-4-乙酰氨基联苯代谢活化中的作用。
Carcinogenesis. 1989 Dec;10(12):2285-91. doi: 10.1093/carcin/10.12.2285.
10
Effect of ascorbic acid on in vitro mutagenicity and in vivo covalent binding of N-hydroxy-2-acetylaminofluorene in the rat.抗坏血酸对大鼠体内N-羟基-2-乙酰氨基芴的体外诱变性和体内共价结合的影响。
Mutat Res. 1980 May;70(3):395-8. doi: 10.1016/0027-5107(80)90030-5.

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Nuclear DNA and Mitochondrial Damage of the Cooked Meat Carcinogen 2-Amino-1-methyl-6-phenylimidazo[4,5-]pyridine in Human Neuroblastoma Cells.2-氨基-1-甲基-6-苯基咪唑[4,5-b]吡啶在人神经母细胞瘤细胞中的核 DNA 和线粒体损伤作为烹饪肉致癌剂。
Chem Res Toxicol. 2023 Aug 21;36(8):1361-1373. doi: 10.1021/acs.chemrestox.3c00109. Epub 2023 Jul 8.
2
Metabolic Activation of the Cooked Meat Carcinogen 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine in Human Prostate.人类前列腺中烹饪肉类致癌剂 2-氨基-1-甲基-6-苯基咪唑[4,5-b]吡啶的代谢激活。
Toxicol Sci. 2018 Jun 1;163(2):543-556. doi: 10.1093/toxsci/kfy060.
3
Characterization and expression of hepatic sulfotransferase involved in the metabolism of N-substituted aryl compounds.
参与N-取代芳基化合物代谢的肝脏磺基转移酶的表征与表达
Environ Health Perspect. 1994 Oct;102 Suppl 6(Suppl 6):99-103. doi: 10.1289/ehp.94102s699.
4
Toxic interactions among environmental pollutants: corroborating laboratory observations with human experience.环境污染物之间的毒性相互作用：用人类经验佐证实验室观察结果。
Environ Health Perspect. 1994 Nov;102 Suppl 9(Suppl 9):11-7. doi: 10.1289/ehp.94102s911.
5
Heterogeneity of rat hepatocytes in bile acid and DBSP transport studied after induction of selective acinar damage by N-hydroxy-2-acetylaminofluorene and carbon tetrachloride.在通过N-羟基-2-乙酰氨基芴和四氯化碳诱导选择性腺泡损伤后，研究大鼠肝细胞在胆汁酸和二溴磺酚（DBSP）转运方面的异质性。
Naunyn Schmiedebergs Arch Pharmacol. 1983 May;322(4):310-8. doi: 10.1007/BF00508348.
6
Binding and repair of 2-acetylaminofluorene adducts in distinct liver cell populations.2-乙酰氨基芴加合物在不同肝细胞群体中的结合与修复
Environ Health Perspect. 1983 Mar;49:87-92. doi: 10.1289/ehp.834987.
7
An understanding of the role of enzyme localization of the liver on metabolite kinetics: a computer simulation.
J Pharmacokinet Biopharm. 1983 Oct;11(5):451-68. doi: 10.1007/BF01062205.
8
Modulation of genotoxic and cytotoxic effects of aromatic amines in monolayers of rat hepatocytes.大鼠肝细胞单层中芳香胺遗传毒性和细胞毒性作用的调节
Cell Biol Toxicol. 1984 Oct;1(1):95-110. doi: 10.1007/BF00125568.
9
Sulfation and glucuronidation as competing pathways in the metabolism of hydroxamic acids: the role of N,O-sulfonation in chemical carcinogenesis of aromatic amines.硫酸化和葡萄糖醛酸化作为异羟肟酸代谢中的竞争途径：N,O-硫酸化在芳香胺化学致癌作用中的作用。
Environ Health Perspect. 1983 Mar;49:27-32. doi: 10.1289/ehp.834927.
10
The metabolic activation and nucleic acid adducts of naturally-occurring carcinogens: recent results with ethyl carbamate and the spice flavors safrole and estragole.天然致癌物的代谢活化与核酸加合物：氨基甲酸乙酯以及调味香料黄樟素和草蒿脑的最新研究结果
Br J Cancer. 1983 Jul;48(1):1-15. doi: 10.1038/bjc.1983.151.