N4-hydroxycytidine: a mutagen specific for AT to GC transitions.
作者信息
Janion C, Glickman B W
出版信息
Mutat Res. 1980 Aug;72(1):43-7. doi: 10.1016/0027-5107(80)90218-3.
PMID:6160396
Abstract
N4-Hydroxycytidine is a mutagen of the base-analog type and one of the products formed by treatment of cytidine with hydroxylamine. In this communication evidence is presented showing that, in contrast with other known base analogs, N4-hydroxycytidine results mainly, if not exclusively, in AT leads to GC transitional alterations in Escherichia coli K12.
摘要
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