Mross K, Mross B, Wolfrum D I, Kohlschütter A
Res Exp Med (Berl). 1980;177(3):245-53. doi: 10.1007/BF01851215.
Lymphocytes from seven patients with malignancies, from seven patients with non-malignancies, and from five healthy persons were incubated with 125I-labeled MBP. Binding of MBP of lymphocytes was monitored from 0.5 to 20h. The binding ranged from 4 to 7% of the total MBP present and remained fairly constant during the first 4h of incubation. It dropped considerably at 20h. Mean percentages of MBP binding were lower in cancer patients than in persons without malignancies. After incubation, the supernates were examined by gel electrophoresis. The electrophoretic pattern was similar in comparing groups with different diagnoses. A considerable loss of MBP in the terminal supernatant (20h) was found. When tested in the electrophoretic mobility test (EM test) with stabilized erythrocytes, supernatant derived from cancer patients produced a somewhat higher mean slowing effect than did superntes from other patients and controls.
来自7名恶性肿瘤患者、7名非恶性肿瘤患者和5名健康人的淋巴细胞与125I标记的髓磷脂碱性蛋白（MBP）一起孵育。在0.5至20小时内监测淋巴细胞对MBP的结合情况。结合量占存在的总MBP的4%至7%，并且在孵育的前4小时内保持相当稳定。在20小时时显著下降。癌症患者中MBP结合的平均百分比低于无恶性肿瘤的人。孵育后，通过凝胶电泳检查上清液。在比较不同诊断组时，电泳图谱相似。发现在终末上清液（20小时）中有相当数量的MBP损失。当用稳定化红细胞进行电泳迁移率试验（EM试验）时，来自癌症患者的上清液产生的平均减慢效应略高于来自其他患者和对照组的上清液。
