Meyer-Estorf G, Keller K, Beck O A, Hochrein H
Z Kardiol. 1980 Jun;69(6):417-20.
In 6 patients with stable cardiac dysrhythmias (ectopic beats) an oral dose of 300 mg propafenone was given in eight-hour intervals for 4-6 days. A significant correlation between serum concentration and prolongation of PQ-time interval was found. Therefore the changes of PQ-time interval can be used for the control of dose of propafenone.
对6例稳定型心律失常(异位搏动)患者,每8小时口服300毫克普罗帕酮,持续4 - 6天。发现血清浓度与PQ间期延长之间存在显著相关性。因此,PQ间期的变化可用于控制普罗帕酮的剂量。