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[大鼠内嗅皮质注射[3H]脯氨酸后内嗅-海马系统经神经物质转运的放射自显影术(作者译)]

[Autoradiography of transneural substance transport in the entorhino-hippocampal system after [3H] proline injection into the entorhinal cortex in rat (author's transl)].

作者信息

Fröhlich J

出版信息

Acta Histochem. 1980;67(1):47-53.

PMID:6160715
Abstract

The entorhinal afferences to Fascia dentata and Stratum lacunoso-moleculare of CA1 could be visualised by means of anterograde axoplasmic transport 5 days after L-[5-3H]-proline injection into the entorhinal cortex. Furthermore, the macromolecule-bound tracer was found in the perikarya of granule cells and mossy fibres as well as in the cell bodies of the CA1 pyramids. These findings indicate that labelled material, released from the axonal terminals of the perforant pathway, is taken up by these neurons.

摘要

在将L-[5-³H]-脯氨酸注入内嗅皮质5天后,通过顺行轴浆运输可观察到内嗅皮质至齿状回和CA1的腔隙-分子层的传入纤维。此外,在颗粒细胞和苔藓纤维的胞体以及CA1锥体神经元的细胞体中发现了与大分子结合的示踪剂。这些发现表明,从穿通通路的轴突终末释放的标记物质被这些神经元摄取。

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