Grisolia J S, Wiederholt W C
Electroencephalogr Clin Neurophysiol. 1980 Dec;50(5-6):375-81. doi: 10.1016/0013-4694(80)90005-x.
Short latency somatosensory evoked potentials (SEPs) were elicited by stimulation at the wrist of median, radial, and ulnar nerves, singly or in combination, using normal subjects. Amplitude of P10 was strikingly lower with radial stimulation than with median stimulation, while ulnar-derived P10 was intermediate in amplitude. This difference probably reflects the antidromic firing of motor fibers contained in median nerves as compared with the superficial branch of radial nerve, which is entirely sensory. Beyond P10, there appear to be no significant differences between median, radial and ulnar-derived SEPs. With simultaneous stimulation of several nerves within one arm, larger potentials were sometimes achieved but with poorer definition of P12 and P14. The clinical utility of radial, ulnar, and median stimulation for localizing peripheral lesions derives from the distinct anatomical pathways of the stimulated fibers through the brachial plexus and from the separable motor and sensory components of P10. SEP is less invasive than EMG; this fact, plus its freedom from sampling error, make it potentially more suitable than conventional EMG for sequentially following a patient's clinical course.
在正常受试者中，通过单独或联合刺激正中神经、桡神经和尺神经的腕部来引出短潜伏期体感诱发电位（SEP）。与正中神经刺激相比，桡神经刺激时P10的波幅显著更低，而尺神经引出的P10波幅则介于两者之间。这种差异可能反映了正中神经中所含运动纤维的逆向放电，与之相比，桡神经浅支完全是感觉性的。在P10之后，正中神经、桡神经和尺神经引出的SEP之间似乎没有显著差异。当同时刺激一侧手臂内的多条神经时，有时会获得更大的电位，但P12和P14的清晰度较差。桡神经、尺神经和正中神经刺激在定位周围病变方面的临床效用源于受刺激纤维通过臂丛的不同解剖路径以及P10可分离的运动和感觉成分。SEP比肌电图（EMG）侵入性小；这一事实，加上其无抽样误差，使其可能比传统EMG更适合于连续跟踪患者的临床病程。
