Radoux D, Lepoint A, Goessens G
Bull Assoc Anat (Nancy). 1980 Jun;64(185):259-66.
Adenosine induces a massive nucleolar disorganization both in chick embryo fibroblasts and Ehrlich ascitic tumour cells in which the fibrillar centre is the only persistent structure. We discuss these observations in term of RNA synthesis inhibition as fibrillar centres are the Nucleolus-Organizing Regions (NOR's).