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人类枕叶癫痫发作扩散至颞叶过程中的神经元放电模式。

Neuronal firing patterns during the spread of an occipital lobe seizure to the temporal lobes in man.

作者信息

Babb T L, Halgren E, Wilson C, Engel J, Crandall P

出版信息

Electroencephalogr Clin Neurophysiol. 1981 Jan;51(1):104-7. doi: 10.1016/0013-4694(81)91513-3.

DOI:10.1016/0013-4694(81)91513-3
PMID:6161774
Abstract

Neuronal recordings from occipital cortex and hippocampus during a seizure originating in the occipital lobe of a patient with an occipito-temporal tumor demonstrated that the visual aura resulted from neuronal activation of medial peristriate and possibly other occipital lobe neurons while the psychomotor automatisms followed 10-20 sec later and were caused by recruitment of hippocampal neurons bilaterally. This confirmed that the complex seizure symptoms were caused by propagation from an occipital lobe focus. The psychomotor symptoms have not recurred for the 6 months since interruption of occipito-temporal connections; however, the spared medial occipital neurons still produce visual auras.

摘要

对一名患有枕颞叶肿瘤患者枕叶发作期间枕叶皮质和海马的神经元记录表明,视觉先兆是由内侧纹周区以及可能的其他枕叶神经元的激活引起的,而精神运动性自动症在10 - 20秒后出现,是由双侧海马神经元的募集导致的。这证实了复杂的癫痫症状是由枕叶病灶的扩散引起的。自枕颞叶连接中断以来的6个月里,精神运动症状未再复发;然而,保留的枕叶内侧神经元仍会产生视觉先兆。

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