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细胞周期中多胺积累与RNA生物合成及含量之间的关系。

Relationship between polyamine accumulation and RNA biosynthesis and content during the cell cycle.

作者信息

Goyns M H

出版信息

Experientia. 1981 Jan 15;37(1):34-5. doi: 10.1007/BF01965553.

DOI:10.1007/BF01965553
PMID:6162673
Abstract

Polyamine accumulation was related to RNA biosynthesis and content during the cell cycle of CHO-K1 and HeLa cells. The highest correlations were observed between polyamine accumulation and RNA content. Feeding, serum-starved cultures of embryonic chick fibroblasts, which exhibit a 3-fold increase in RNA content, demonstrated that RNA content was most closely paralleled by spermidine content.

摘要

在CHO-K1和HeLa细胞的细胞周期中，多胺积累与RNA生物合成及含量相关。多胺积累与RNA含量之间观察到最高的相关性。对胚胎鸡成纤维细胞进行血清饥饿培养并喂食，其RNA含量增加了3倍，这表明亚精胺含量与RNA含量最为密切相关。

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本文引用的文献

1
Determination of nucleic acids in animal tissues.动物组织中核酸的测定。
J Biol Chem. 1955 May;214(1):59-70.
2
CLONAL GROWTH OF MAMMALIAN CELLS IN A CHEMICALLY DEFINED, SYNTHETIC MEDIUM.哺乳动物细胞在化学成分明确的合成培养基中的克隆生长
Proc Natl Acad Sci U S A. 1965 Feb;53(2):288-93. doi: 10.1073/pnas.53.2.288.
3
ISOLATION OF A SOLUBLE RNA POLYMERASE FROM RAT TESTIS.从大鼠睾丸中分离出一种可溶性RNA聚合酶。
病毒在自身免疫性疾病中的影响：扩展“X染色体 - 核仁联系”假说
Front Immunol. 2017 Nov 28;8:1657. doi: 10.3389/fimmu.2017.01657. eCollection 2017.
4
Epigenetics and autoimmune diseases: the X chromosome-nucleolus nexus.表观遗传学与自身免疫性疾病：X 染色体-核仁连接。
Front Genet. 2015 Feb 16;6:22. doi: 10.3389/fgene.2015.00022. eCollection 2015.
Nature. 1964 Jul 11;203:150-1. doi: 10.1038/203150a0.
4
ENZYMATIC SYNTHESIS OF RIBONUCLEIC ACID. II. PROPERTIES OF THE DEOXYRIBONUCLEIC ACID-PRIMED REACTION WITH MICROCOCCUS LYSODEIKTICUS RIBONUCLEIC ACID POLYMERASE.核糖核酸的酶促合成。II. 用溶壁微球菌核糖核酸聚合酶进行的脱氧核糖核酸引发反应的性质
J Biol Chem. 1964 Jan;239:175-85.
5
Amino acid metabolism in mammalian cell cultures.哺乳动物细胞培养中的氨基酸代谢
Science. 1959 Aug 21;130(3373):432-7. doi: 10.1126/science.130.3373.432.
6
Effect of cell synchronization techniques on polyamine content of HeLa cells.细胞同步化技术对HeLa细胞多胺含量的影响。
Experientia. 1980 Aug 15;36(8):936-7. doi: 10.1007/BF01953801.
7
Effect of polyamines on ribosomal RNA synthesis during sea urchin development.多胺对海胆发育过程中核糖体RNA合成的影响。
Exp Cell Res. 1968 Jun;50(3):671-4. doi: 10.1016/0014-4827(68)90434-5.
8
Mitotic synchrony in mammalian cells treated with nitrous oxide at high pressure.高压下一氧化二氮处理的哺乳动物细胞中的有丝分裂同步性。
Science. 1968 May 17;160(3829):774-6. doi: 10.1126/science.160.3829.774.
9
[Microdetermination of spermine and spermidine as 1-dimethylaminonaphthalene-5-sulfonic acid derivtives].[作为1-二甲基氨基萘-5-磺酸衍生物的精胺和亚精胺的微量测定]
Hoppe Seylers Z Physiol Chem. 1967 Oct;348(10):1285-90.
10
The biochemical role of naturally occurring polyamines in nucleic acid synthesis.天然存在的多胺在核酸合成中的生化作用。
Biol Rev Camb Philos Soc. 1970 Feb;45(1):1-27. doi: 10.1111/j.1469-185x.1970.tb01073.x.