Mouttet M E, Béchet J M, Montagnier L
Intervirology. 1980;14(2):78-83. doi: 10.1159/000149166.
Untransformed and hamster sarcoma virus-transformed BHK-21 cells were compared for their ability to support productive infection with herpes simplex virus type 1. In both types of cells, infection with herpes simplex virus resulted in a lytic, productive cycle. However, inhibition of host cell RNA and DNA synthesis, transcription and replication of viral DNA, and production of infectious virus began earlier and reached higher levels in transformed cells.
对未转化的和经仓鼠肉瘤病毒转化的BHK - 21细胞支持单纯疱疹病毒1型有效感染的能力进行了比较。在这两种类型的细胞中，单纯疱疹病毒感染均导致裂解性的有效复制周期。然而，宿主细胞RNA和DNA合成、病毒DNA转录和复制以及传染性病毒产生的抑制在转化细胞中开始得更早且达到更高水平。
