与培养的鸡神经元和非神经元细胞中10纳米细丝相关的不同蛋白质。

Different proteins associated with 10-nanometer filaments in cultured chick neurons and nonneuronal cells.

作者信息

Bennett G S, Tapscott S J, Kleinbart F A, Antin P B, Holtzer H

出版信息

Science. 1981 May 1;212(4494):567-9. doi: 10.1126/science.6163217.

Abstract

A protein of molecular size 180 kilodaltons is associated with 10-nanometer filaments in neurons and is immunologically distinct from smaller putative neurofilament subunits and from 10-nanometer filament proteins in nonneuronal cells, such as myotubes and fibroblasts. Neurons do not contain vimentin, the major filament protein in many other cells, including the nonneuronal cells in cultures of neural tissue.

摘要

一种分子大小为180千道尔顿的蛋白质与神经元中的10纳米细丝相关联，并且在免疫方面与较小的假定神经丝亚基以及非神经元细胞（如肌管和成纤维细胞）中的10纳米细丝蛋白不同。神经元不含波形蛋白，波形蛋白是许多其他细胞（包括神经组织培养中的非神经元细胞）中的主要细丝蛋白。