Ledesma E J, Evans J T, Yoon J, Bruno S, Mittelman A
Surg Gynecol Obstet. 1981 Apr;152(4):451-2.
Ligation of the hepatic artery has been successfully used in the management of massive bleeding, secondary to hepatic trauma, and in the treatment of metastatic neoplastic disease. The indications for a concomitant cholecystectomy are less well defined. It is generally accepted that cholecystectomy should be performed when ligation is used to control bleeding. In our study, ligation of the hepatic artery was performed, leaving the gallbladder in situ. At autopsy, no pathologic process could be detected in the gallbladder. Microscopic analysis showed fibrosis in the mucosal surface, mild chronic inflammation and nonspecific mononuclear infiltration. We conclude that the changes are insufficient to warrant the removal of a normal gallbladder when ligation of the hepatic artery is performed as treatment for neoplastic disease.
肝动脉结扎术已成功应用于治疗因肝外伤引起的大量出血以及转移性肿瘤疾病。同时进行胆囊切除术的适应证尚不太明确。一般认为，当使用结扎术控制出血时应进行胆囊切除术。在我们的研究中，进行了肝动脉结扎术，而将胆囊留在原位。尸检时，未在胆囊中检测到病理过程。显微镜分析显示黏膜表面有纤维化、轻度慢性炎症和非特异性单核细胞浸润。我们得出结论，当进行肝动脉结扎术作为肿瘤疾病的治疗方法时，这些变化不足以保证切除正常胆囊。
