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[糖尿病患者血浆β-血小板球蛋白水平的测定]

[Determination of the level of plasma beta-thromboglobulin in diabetes].

作者信息

Stoltz J F, Voisin P, Drouin P, Pointel J P, Benisti G

出版信息

Biomedicine. 1980;33(6):194-6.

PMID:6163487
Abstract

Plasma beta-TG was measured radioimmunoassay on 23 controls and 84 diabetics. The diabetic patients were divided in three groups: I. Patients without complications, insulin-dependants or not. II. Patients with retinopathy, without severe complications. III. Patients with retinopathy and distal arteritis. beta-TG level in control group is 23,4 +/- 7,6 ng/ml and is comparable with literature. An important increase of beta-TG average level was observed for the three diabetic groups. The almost equal increase between groups I and II could be explained by a comparable hyperagregability, as previously described in diabetes. There could be an increase of hyperagregability with arteritis appearance, and a increase of beta-TG release. Correlation between these two parameters remains to be demonstrated.

摘要

采用放射免疫分析法对23名对照者和84名糖尿病患者测定血浆β-血小板球蛋白(beta-TG)。糖尿病患者分为三组:I. 无并发症患者,无论是否依赖胰岛素。II. 患有视网膜病变但无严重并发症的患者。III. 患有视网膜病变和远端动脉炎的患者。对照组的β-血小板球蛋白水平为23.4±7.6 ng/ml,与文献报道相当。观察到三组糖尿病患者的β-血小板球蛋白平均水平均显著升高。I组和II组之间几乎相同的升高可通过类似的高聚集性来解释,如先前在糖尿病中所描述的那样。随着动脉炎的出现,高聚集性可能增加,β-血小板球蛋白释放也会增加。这两个参数之间的相关性仍有待证实。

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