Bazhenov Iu I, Sydykov B K
Fiziol Zh SSSR Im I M Sechenova. 1981 Feb;67(2):294-8.
The influence of thyroid hormone in thermogenesis of animals adapting to high altitude for different periods were studied in white rats. The adaptation to high altitude hypoxia decreased reaction of the organism to cold. The antithyroid injection of mercazolil potentiated the hypoxia action in cold thermogenesis and lowered sharply the body temperature stability in cooling. The analogous injection of triiodthyronine reduced the hypoxia influence on the thermogenesis and increased the contribution of the contractile heat production in the thermoregulative metabolism. The data suggest that one of the reasons of the low heat effect of the muscle contraction in adaptation to hypoxia may be the functional weakening of the thyroid gland.
在白鼠身上研究了甲状腺激素对适应不同时期高海拔环境的动物产热的影响。对高海拔缺氧的适应降低了机体对寒冷的反应。注射抗甲状腺药物甲巯咪唑增强了缺氧对冷产热的作用，并急剧降低了降温过程中体温的稳定性。注射类似物三碘甲状腺原氨酸可减少缺氧对产热的影响，并增加收缩产热在体温调节代谢中的作用。数据表明，适应缺氧时肌肉收缩热效应低的原因之一可能是甲状腺功能减弱。
