Rufli T, Mumcuoglu Y, Cajacob A, Büchner S
Dermatologica. 1981;162(1):12-26.
In 16 out of 18 patients with rosacea, mites of the species, Demodex folliculorum were isolated in mostly great numbers from lesions of the facial skin. In patients with perioral dermatitis, the mite was demonstrated in 17 out of 29 patients. All patients, however, including those where no mites were found, could be completely cured by nightly application of hexachlorocyclohexane 0.25% (Jacutin). The average treatment time was 7 weeks for rosacea and 5 weeks for perioral dermatitis. 2 patients with rosacea and 4 patients with perioral dermatitis relapsed, but cleared again after treatment was repeated. The initial flare-up of the dermatitis, which is observed regularly after starting the Jacutin-therapy, is described. Quantitative aspects of Demodex infestation and its histopathological alterations are discussed in relation to present-day knowledge.
在18例酒渣鼻患者中的16例中，从面部皮肤病变处大量分离出毛囊蠕形螨。在口周皮炎患者中，29例中有17例发现了螨虫。然而，所有患者，包括未发现螨虫的患者，通过每晚涂抹0.25%的六氯环己烷（雅库廷）均可完全治愈。酒渣鼻的平均治疗时间为7周，口周皮炎为5周。2例酒渣鼻患者和4例口周皮炎患者复发，但再次治疗后又消退了。描述了开始雅库廷治疗后经常观察到的皮炎初始 flare-up 情况。结合当今知识讨论了蠕形螨感染的定量方面及其组织病理学改变。
