[支气管哮喘患者血清免疫球蛋白E水平]
[Serum immunoglobulin E level in bronchial asthma].
作者信息
Denchev K, Radkov M, Lipcheva N
出版信息
Vutr Boles. 1976;15(3):88-91.
Serum immunoglobulin E level was determined in 50 patients with bronchial asthma, treated in the out-patients department and clinical conditions at the Faculty Hospital--Varna. The quantitative determination of immunoglobulin E was carried out by radial immunodiffusion according to Mancini with monospecific anti-IgE globulin serum from Behringswerke (GFR). A considerable elevation of immunoglobulin E in the patients' sera was found, at an average of 394 IU (control 124 IU). A discrepancy in serum immunoglobulin E level was established with the different clinical forms of asthma. The highest are the values with infectious-allergic astmha-424 IU. High are the values both in the treated and not-treated with corticosteroids, without an essential difference between the two patient groups. Some of the rest immunoglobulins showed also an elevationppIgG 2620 mg% and IgA 366 mg%.
对在瓦尔纳市大学医院门诊部接受治疗的50例支气管哮喘患者测定了血清免疫球蛋白E水平及临床状况。根据曼奇尼法，使用来自贝林格werke公司（德国）的单特异性抗IgE球蛋白血清，通过放射免疫扩散法对免疫球蛋白E进行定量测定。发现患者血清中的免疫球蛋白E显著升高，平均为394 IU（对照组为124 IU）。在哮喘的不同临床类型中，血清免疫球蛋白E水平存在差异。感染性过敏性哮喘患者的数值最高——424 IU。接受和未接受皮质类固醇治疗的患者数值均较高，两组患者之间无本质差异。其他一些免疫球蛋白也有所升高——IgG为2620 mg%，IgA为366 mg%。
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