Shrosbree R D, Engel P
S Afr Med J. 1981 Jun 13;59(25):902-4.
Twenty-five patients with 35 bedsores were treated with dextranomer (Debrisan; Adcock Ingram) applied topically to the ulcers. Fourteen patients had ulcers which penetrated fascia, muscle and bone, 4 had superficial ulcers and 2 had discharging sinuses. Most of the severe ulcers healed rapidly and were cleansed and ready for surgery at an average of 14.6 days. The superficial ulcers were completely healed within 3 weeks. Treatment of the sinuses with dextranomer using a catheter/syringe technique resulted in wound closure within 28 days. In a representative sample of 12 patients in whom the surface area of the ulcers was measured by means of a planimeter, there was a median reduction in surface area of 44.8% by the 2nd week (P=0,0002) and 79% (P=0,001) at the end of the 4th week. The median percentage reduction in depth was 66.7% (P=0,008) at the end of the 4th week.
25例患有35处褥疮的患者接受了葡聚糖omer（Debrisan；Adcock Ingram）局部应用于溃疡的治疗。14例患者的溃疡穿透了筋膜、肌肉和骨骼，4例有浅表溃疡，2例有脓性窦道。大多数严重溃疡愈合迅速，平均14.6天后清洁完毕并可进行手术。浅表溃疡在3周内完全愈合。使用导管/注射器技术用葡聚糖omer治疗窦道，28天内伤口闭合。在通过面积计测量溃疡表面积的12例患者的代表性样本中，到第2周时表面积中位数减少44.8%（P=0.0002），第4周末减少79%（P=0.001）。第4周末深度减少的中位数百分比为66.7%（P=0.008）。
