Schwarz H P, Aiginger P, Kuzmits R
Acta Med Austriaca. 1981;8(1):22-5.
Fibrinogen degradation products could be detected frequently in patients with metastasized tumour disease. Plasminogen, antithrombin III and fibrinogen were not found to be elevated. The proteinase inhibitors alpha 2-macroglobulin, alpha 1-antitrypsin and C1-esterase inactivator were measured before and after chemotherapy. alpha 1-antitrypsin and C1-esterase inactivator were elevated in patients with pulmonary and/or retroperitoneal metastases. Regardless of the stage of the tumour disease serum level of alpha 1-antitrypsin and C1-esterase inactivator in increased under cytotoxic chemotherapy.
在转移性肿瘤疾病患者中，纤维蛋白原降解产物常可被检测到。未发现纤溶酶原、抗凝血酶III和纤维蛋白原升高。在化疗前后测定了蛋白酶抑制剂α2-巨球蛋白、α1-抗胰蛋白酶和C1酯酶抑制剂。α1-抗胰蛋白酶和C1酯酶抑制剂在有肺和/或腹膜后转移的患者中升高。无论肿瘤疾病处于何阶段，在细胞毒性化疗作用下，α1-抗胰蛋白酶和C1酯酶抑制剂的血清水平都会升高。
