一只狗的己烯雌酚中毒

Stilboestrol toxicity in a dog.

作者信息

Mills J N, Slatter D H

出版信息

Aust Vet J. 1981 Jan;57(1):39-42. doi: 10.1111/j.1751-0813.1981.tb07083.x.

DOI:10.1111/j.1751-0813.1981.tb07083.x

Abstract

A case of stilboestrol toxicity is described in a dog which was treated for prostatic hyperplasia with stilboestrol dipropionate (10 mg) daily for 5 days. An initial anaemia and thrombocytopaenia of 19,500/microliters was recorded on day 11, and a severe leukocytosis of 125,300/microliters on day 15 was followed by a precipitous drop to 8,400/microliters on day 21. The dog received antibiotic treatment for concurrent peritonitis and prostatitis/cystitis between days 7 and 15. The dog died on day 41 with marrow aplasia.

摘要

本文描述了一例己烯雌酚中毒的犬病例。该犬因前列腺增生，每日接受丙酸己烯雌酚（10毫克）治疗，持续5天。第11天记录到初始贫血和血小板减少，血小板计数为19,500/微升，第15天出现严重白细胞增多，计数为125,300/微升，随后在第21天急剧降至8,400/微升。该犬在第7天至第15天期间因并发腹膜炎和前列腺炎/膀胱炎接受了抗生素治疗。该犬于第41天死于骨髓再生障碍。