Pies R
Arch Intern Med. 1981 Jul;141(8):1087.
A 28-year-old woman received a single course of corticosteroids for treatment of ulcerative colitis. She subsequently became depressed; shortly thereafter, signs of mania developed. Despite discontinuation of corticosteroid therapy, the patient has had five bouts of mania, closely followed by severe depression, in the past 1 1/2 years. This seems to be the first case of persistent bipolar illness after exogenous steroid administration.
一名28岁女性接受了一个疗程的皮质类固醇药物治疗溃疡性结肠炎。随后她出现了抑郁症状；不久之后，又出现了躁狂迹象。尽管停用了皮质类固醇治疗，但在过去的1年半时间里，该患者已发作了5次躁狂，随后紧接着是严重抑郁。这似乎是外源性类固醇给药后出现持续性双相情感障碍的首例病例。
