SGC (SIF) cells in autonomic ganglion: evidence for a possible secretion of their content into the blood vessels.

Authors described signs of extrusion of granular vesicles from the SCG (SIF) cells in the inferior mesenteric ganglion of the dog. The granular vesicles were found in extracellular space as well as in the blood capillary lumen. Beside this, large number of granular vesicles were found in the cytoplasm of endothelial cells of blood capillary, mainly in places of close contact between the SGC cell and the endothelial cell of the capillary. These findings strongly suggest secretory function be a primary role of SGC cells in inferior mesenteric ganglion and would explain the rich vascularisation of the SGC cell groups.