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黑质在杏仁核阵发性活动控制中的作用。

The role of the substantia nigra in the control of amygdaloid paroxysmal activity.

作者信息

Amato G, Sorbera F, Crescimanno G, La Grutta V

出版信息

Arch Int Physiol Biochim. 1981 May;89(2):91-5. doi: 10.3109/13813458109073987.

DOI:10.3109/13813458109073987
PMID:6167236
Abstract

Both in acute and chronic cats focal paroxysmal activity evoked in the ventro-basal complex of the amygdala has been inhibited by substantia nigra conditioning stimulation, to a greater extent, than by caudate nucleus activation. Injection of kainic acid into substantia nigra resulted in the disappearance of the caudate inhibition. It is suggested that the final control, exerted by the striatum on the amygdaloid seizures, occurs by means of the substantia nigra.

摘要

在急性和慢性猫中,杏仁核腹侧基底复合体诱发的局灶性阵发性活动,被黑质条件刺激抑制的程度,比被尾状核激活抑制的程度更大。向黑质注射 kainic 酸导致尾状核抑制消失。提示纹状体对杏仁核癫痫发作的最终控制是通过黑质实现的。

相似文献

1
The role of the substantia nigra in the control of amygdaloid paroxysmal activity.黑质在杏仁核阵发性活动控制中的作用。
Arch Int Physiol Biochim. 1981 May;89(2):91-5. doi: 10.3109/13813458109073987.
2
Relationship between the striatal system and amygdaloid paroxysmal activity.纹状体系统与杏仁核阵发性活动之间的关系。
Exp Neurol. 1982 Sep;77(3):492-504. doi: 10.1016/0014-4886(82)90223-0.
3
[Effects of conditioning stimulation of the substantia nigra on the epileptic activity of the cat amygdala].[黑质条件刺激对猫杏仁核癫痫活动的影响]
Boll Soc Ital Biol Sper. 1981 Sep 30;57(18):1901-4.
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Abortive amygdaloid kindled seizures following microinjection of gamma-vinyl-GABA in the vicinity of substantia nigra in rats.大鼠黑质附近微量注射γ-乙烯基-GABA后杏仁核点燃癫痫发作的中止
Neurosci Lett. 1983 Mar 28;36(1):69-74. doi: 10.1016/0304-3940(83)90488-3.
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[Different effects of conditioning stimulation of the caudate nucleus and globus pallidus on the paroxysmal activity of the cat amygdala].
Boll Soc Ital Biol Sper. 1981 Sep 30;57(18):1896-900.
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[Effects of kainic acid injection into the substantia nigra on the paroxysmal amygdaloid phenomena].向黑质注射海藻酸对阵发性杏仁核现象的影响
Boll Soc Ital Biol Sper. 1984 Feb 28;60(2):369-74.
7
Functional changes in the caudate and accumbens nuclei during amygdaloid and hippocampal seizure development in kindled cats.
Folia Psychiatr Neurol Jpn. 1977;31(3):501-12. doi: 10.1111/j.1440-1819.1977.tb02640.x.
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Progressive pathology of the caudate nucleus, the substantia nigra pars reticulata and the deeper layers of the colliculus superior: acute behavioural and metabolic effects of intrastriatal kainic acid.尾状核、黑质网状部和上丘深层的进行性病理学:纹状体内注射 kainic 酸的急性行为和代谢效应。
Neuroscience. 1989;28(1):159-69. doi: 10.1016/0306-4522(89)90240-6.
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Modifications induced on the amygdaloid paroxysmal activity by entopeduncolar or nigral injection of kainic acid, in the cat.猫杏仁核阵发性活动因内苍白球或黑质注射红藻氨酸所诱发的改变
Arch Int Physiol Biochim. 1983 Dec;91(5):399-404. doi: 10.3109/13813458309067986.
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Anticonvulsant action of 2-amino-7-phosphonoheptanoic acid in the substantia nigra.2-氨基-7-膦酰庚酸在黑质中的抗惊厥作用。
Eur J Pharmacol. 1984 Oct 30;106(1):175-9. doi: 10.1016/0014-2999(84)90692-7.

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Sustained seizures cause circumscribed cerebral changes in glial fibrillary acidic protein, neurofilament and laminin immunofluorescence.持续性癫痫发作会导致胶质纤维酸性蛋白、神经丝和层粘连蛋白免疫荧光出现局限性脑改变。
Exp Brain Res. 1987;69(1):155-66. doi: 10.1007/BF00247038.