Hirshorn M S, Holley L K, Hales J R, Money D K, Young F A, Spector M, Wickham G G
Pacing Clin Electrophysiol. 1981 Jul;4(4):380-90. doi: 10.1111/j.1540-8159.1981.tb03716.x.
Several different materials, including one which was porous, were studied to assess their properties as pacemaker electrode tips. Leads were implanted in sheep for periods up to one year. Electrical measurements were made during the implant period and histopathological examination performed after sacrifice. Although titanium vapor-deposited carbon, and silver did not lower the chronic stimulation threshold below that of platinum, their electrical characteristics were within generally acceptable limits. Zinc evoked a severe tissue reactions and a high threshold. Porous titanium alloy electrodes demonstrated reduced dislodgement, more frequent attachment and a lower sensing impedance than other electrodes.
研究了几种不同的材料,包括一种多孔材料,以评估它们作为起搏器电极尖端的性能。将导线植入绵羊体内长达一年。在植入期间进行电学测量,并在处死动物后进行组织病理学检查。尽管钛蒸镀碳和银并没有将慢性刺激阈值降低到低于铂的水平,但其电学特性总体上在可接受的范围内。锌引发了严重的组织反应和高阈值。多孔钛合金电极比其他电极表现出更少的移位、更频繁的附着以及更低的感知阻抗。