Ruffmann R, Seifert R, Ross H, Haass H G
HNO. 1981 Aug;29(8):270-3.
12 patients with far advanced head and neck squamous cell carcinoma, no longer apt to curative therapy, were submitted to palliative chemotherapy by V-B-M- schedule. Palliative therapy has great importance in this type of tumor, which due to its localisation causes terrible deformities and thus psychologically and sociologically forms a heavy burden. Nearly all patients became free of pain, exulcerations could be reduced, successfully general status could be improved. Due to an out patient regimen patients remained at home. Most of all this last circumstance helped to realize true palliative therapy; toxicity was mild.
12例头颈部晚期鳞状细胞癌患者,不再适合进行根治性治疗,采用V-B-M方案进行姑息化疗。姑息治疗在这类肿瘤中具有重要意义,由于其位置特殊,会导致严重畸形,从而在心理和社会层面造成沉重负担。几乎所有患者都不再疼痛,溃疡得以减轻,全身状况得到成功改善。由于采用门诊治疗方案,患者可居家治疗。最重要的是,这最后一点有助于实现真正的姑息治疗;毒性较轻。