Ikić D, Brnobić A, Lipozencić J, Malecek J, Smerdel S, Delimar N, Soos E
Int J Clin Pharmacol Ther Toxicol. 1981 Oct;19(10):450-2.
Human leukocyte interferon (HLI) incorporated in ointment (4,000 units/g) applied topically for 4 weeks induced the process of "scavenging" granulation and epithelialization of stasis ulcers. This therapy had a better effect than that of the other combined local and general therapy also given in the study. A comparison of the effects of both therapies was made on nine pairs of stasis ulcers. A favorable effect of HLI on granulation and epithelialization was observed in a patient with deep burns, who had been given HLI topically in the form of powder and solution. This type of HLI activity calls for further clinical trials, especially as regards deep burns.
将含人白细胞干扰素（HLI）的软膏（4000单位/克）局部应用4周，可诱导淤积性溃疡的“清除”肉芽形成和上皮化过程。该疗法比本研究中采用的其他局部和全身联合疗法效果更好。对9对淤积性溃疡进行了两种疗法效果的比较。在一名深度烧伤患者中观察到HLI对肉芽形成和上皮化有良好作用，该患者接受了粉末和溶液形式的HLI局部治疗。HLI的这种活性需要进一步进行临床试验，尤其是针对深度烧伤。
