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[抗坏血酸制剂对烧伤动物组织中某些碳水化合物代谢指标的影响]

[Effect of ascorbic acid preparations on certain indices of carbohydrate metabolism in tissues of animals with burns].

作者信息

Gudé Z Zh, Shershun G G

出版信息

Ukr Biokhim Zh (1978). 1981 Sep-Oct;53(5):97-100.

PMID:6170143
Abstract

The glucose content and glucokinase, amylase, hyaluronidase activities were determined in skin of guinea pigs after a burn. It is shown that in the wound focus the amylase and hyaluronidase activities increase, and the activity of glucokinase decreases, the content of glucose grows. Application of ascorbic acid and galascorbin as remedies induces a decrease in the intensity of hydrolytic processes and improves the glucose utilization, particularly with galascorbin introduction. This may evidence for the predominance of reparative processes in the burn area and improvement of their supply with energy.

摘要

测定了豚鼠烧伤后皮肤中的葡萄糖含量以及葡萄糖激酶、淀粉酶、透明质酸酶的活性。结果表明,在伤口部位,淀粉酶和透明质酸酶的活性增加,葡萄糖激酶的活性降低,葡萄糖含量增加。应用抗坏血酸和半胱氨酸作为药物可降低水解过程的强度并改善葡萄糖的利用,尤其是在引入半胱氨酸时。这可能证明烧伤区域修复过程占主导地位且能量供应得到改善。

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