Lagoutte F
J Fr Ophtalmol. 1981;4(6-7):531-9.
Analysis of clinical data and reports in the published literature are employed to develop a physiopathological explanation for corneal neovascularisation, based on a chain reaction in which inflammation and hypoxia play essential roles. The possible advantages and disadvantages that result from this neovascularisation are analysed. There is no fundamental reason for the administration of antivascular therapy alone, and treatment should be directed towards the inflammatory process, which is the cause of the neovascularisation and the opacities. By reducing or suppressing the inflammatory chain reaction it is then possible to break the vicious circle of a possible self-supporting affection.
通过分析已发表文献中的临床数据和报告,基于炎症和缺氧在其中起关键作用的连锁反应,对角膜新生血管形成作出病理生理学解释。分析了这种新生血管形成所带来的可能利弊。单独进行抗血管治疗没有根本依据,治疗应针对炎症过程,因为炎症是新生血管形成和混浊的原因。通过减少或抑制炎症连锁反应,进而有可能打破可能出现的自身持续病变的恶性循环。