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人类股外侧肌和腓肠肌。组织化学与生物化学比较分析。

Human vastus lateralis and gastrocnemius muscles. A comparative histochemical and biochemical analysis.

作者信息

Green H J, Daub B, Houston M E, Thomson J A, Fraser I, Ranney D

出版信息

J Neurol Sci. 1981 Nov-Dec;52(2-3):201-10. doi: 10.1016/0022-510x(81)90005-8.

DOI:10.1016/0022-510x(81)90005-8
PMID:6171618
Abstract

Two muscles involved in locomotion the vastus lateralis and the gastrocnemius, were compared on a variety of histochemical an biochemical properties. Ten active males, age 20 - 24 years, served as subjects. Fibre type distributions, type I, type IIA and type IIB, as determined from samples extracted by muscle biopsy were similar in both muscles. In addition, no significant difference (p greater than 0.05) was found between fibre types in each muscle for fibre size, relative area, capillaries per fibre and the ratio of capillaries per fibre area. The activities of a number of enzymes representative of energy supplying pathways - the citric acid cycle (succinate dehydrogenase, SHD; beta-hydroxyacyl CoA dehydrogenase, HADH), glycogenolysis (total phosphorylase, PHOSP), glycolysis (phosphofructokinase, PFK) - were of similar magnitude between the two muscles. The only exception noted was for the activity of a glycolytic enzyme, lactate dehydrogenase, LDH, where a 16% higher value was observed in the vastus lateralis. The close degree of homogeneity displayed between these two muscles may be of significance in providing for a functional synchrony to occur in locomotor activities of varying intensity.

摘要

对参与运动的两块肌肉——股外侧肌和腓肠肌——的多种组织化学和生化特性进行了比较。十名年龄在20至24岁之间的活跃男性作为受试者。通过肌肉活检提取的样本确定,两块肌肉中I型、IIA型和IIB型纤维类型分布相似。此外,每块肌肉中各纤维类型在纤维大小、相对面积、每根纤维的毛细血管数量以及每根纤维面积的毛细血管比例方面均未发现显著差异(p大于0.05)。代表能量供应途径的多种酶——柠檬酸循环(琥珀酸脱氢酶,SHD;β-羟酰基辅酶A脱氢酶,HADH)、糖原分解(总磷酸化酶,PHOSP)、糖酵解(磷酸果糖激酶,PFK)——的活性在两块肌肉之间相似。唯一的例外是糖酵解酶乳酸脱氢酶(LDH)的活性,股外侧肌中的该活性值高出16%。这两块肌肉之间显示出的高度同质性程度对于在不同强度的运动活动中实现功能同步可能具有重要意义。

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