Malikov U M, Panov A N
Fiziol Zh SSSR Im I M Sechenova. 1981 Oct;67(10):1506-10.
RNA and protein contents in glial and neuronal cells of nucleus raphé dorsalis (NRD) increased by 23 and 31%, resp., following the 24-hr sleep deprivation; within 48 hrs the RNA content attained the normal level, the protein content being lower than normal by 21%. In neurons of nucleus raphé pontis (NRP) the macromolecules contents per cell remained unaltered at the first period of the sleep deprivation and elevated by 30% by the end of the second period. Metabolic changes in gliocytes were parallel to this. The findings suggest exhaustion of functional abilities of the NRD neurons in sleep deprivation as opposed to the NRP neurons.
在24小时睡眠剥夺后，中缝背核（NRD）的神经胶质细胞和神经元中的RNA和蛋白质含量分别增加了23%和31%；在48小时内，RNA含量恢复到正常水平，而蛋白质含量比正常水平低21%。在中缝脑桥核（NRP）的神经元中，在睡眠剥夺的第一阶段，每个细胞的大分子含量保持不变，到第二阶段结束时增加了30%。神经胶质细胞的代谢变化与此平行。这些发现表明，与NRP神经元相反，睡眠剥夺会使NRD神经元的功能能力耗尽。
