[Concentration of nucleic acids and proteins in neurons and gliocytes of rat raphe nuclei following total sleep deprivation in a cylindrical treadmill].

RNA and protein contents in glial and neuronal cells of nucleus raphé dorsalis (NRD) increased by 23 and 31%, resp., following the 24-hr sleep deprivation; within 48 hrs the RNA content attained the normal level, the protein content being lower than normal by 21%. In neurons of nucleus raphé pontis (NRP) the macromolecules contents per cell remained unaltered at the first period of the sleep deprivation and elevated by 30% by the end of the second period. Metabolic changes in gliocytes were parallel to this. The findings suggest exhaustion of functional abilities of the NRD neurons in sleep deprivation as opposed to the NRP neurons.