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血管周围P物质:在哺乳动物软脑膜血管中的存在与分布

Perivascular substance P: occurrence and distribution in mammalian pial vessels.

作者信息

Uddman R, Edvinsson L, Owman C, Sundler F

出版信息

J Cereb Blood Flow Metab. 1981;1(2):227-32. doi: 10.1038/jcbfm.1981.24.

DOI:10.1038/jcbfm.1981.24
PMID:6173392
Abstract

Nerve fibres containing immunoreactive substance P (SP) were demonstrated in the wall of cerebral blood vessels of several mammalian species. Pial arteries of cat and guinea-pig were richly supplied with SP nerve fibres, while those of rat, rabbit, pig, and man had a moderate number. SP fibres were more numerous in pial vessels belonging to the rostral parts of the circle of Willis as compared to more caudally located blood vessels. In cat and guinea-pig, blood vessels in the choroid plexus were surrounded by few SP nerve fibres; also spinal cord blood vessels of cat contained few such fibres.

摘要

在几种哺乳动物的脑血管壁中发现了含有免疫反应性P物质(SP)的神经纤维。猫和豚鼠的软脑膜动脉有丰富的SP神经纤维供应,而大鼠、兔、猪和人的软脑膜动脉则有中等数量的SP神经纤维。与位于更尾侧的血管相比, Willis环前部软脑膜血管中的SP纤维更多。在猫和豚鼠中,脉络丛中的血管周围只有少量SP神经纤维;猫的脊髓血管中也含有少量此类纤维。

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