睡眠呼吸暂停综合征患者脑脊液中的3',5'-环磷酸腺苷、5-羟吲哚乙酸和高香草酸
Cerebrospinal fluid adenosine 3',5'-monophosphate, 5-hydroxyindoleacetic acid and homovanillic acid in patients with sleep apnoea syndrome.
作者信息
Cramer H, Warter J M, Renaud B, Krieger J, Marescaux C H, Hammers R
出版信息
J Neurol Neurosurg Psychiatry. 1981 Dec;44(12):1165-7. doi: 10.1136/jnnp.44.12.1165.
Abstract
Adenosine 3',5'-monophosphate (cyclic AMP), 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) were determined in the cerebrospinal fluid of patients with respiratory disorder and hypersomnia and in control patients. Patients with the sleep apnoea syndrome confirmed polygraphically showed elevated levels of cyclic AMP and 5-HIAA. Cyclic AMP levels were inversely correlated with arterial Po(2), measured under resting conditions. The level of HVA also was raised, but the change was not statistically significant.
摘要
对患有呼吸障碍和嗜睡症的患者以及对照患者的脑脊液中的3',5'-单磷酸腺苷（环磷腺苷）、5-羟吲哚乙酸（5-HIAA）和高香草酸（HVA）进行了测定。经多导睡眠图证实患有睡眠呼吸暂停综合征的患者，其环磷腺苷和5-HIAA水平升高。环磷腺苷水平与静息状态下测得的动脉血氧分压呈负相关。HVA水平也有所升高，但变化无统计学意义。
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