Gădăleanu V
Morphol Embryol (Bucur). 1981 Jul-Sep;27(3):219-25.
The spleens sampled at necropsy of 221 children with acute primary and secondary bronchopulmonary inflammations were characterized by the hyperplasia of lymphoid follicles and plasma cells in 37 per cent of the cases, only a few of them with a multilayered organization of follicles, and by lymphoid depletion in 19 per cent of the cases. The remainder presented small unorganized lymphoid follicles of the primary type, some cases being remarkable by their nodules with a "core" of "epithelioid pattern". The pyroninophilic reactions of high intensity were preponderant in bronchopneumonia of the primary type, but unlike the lung and hilar-tracheobronchial lymph nodes, in spleen there were no differences concerning the two value groups of reactions between the primary pneumonia cases with or without associated extrapulmonary inflammations. Immunofluorescence evidenced, in decreasing order, all the three classes of immunoglobulins: IgM, IgG and IgA.
对221例患有急性原发性和继发性支气管肺炎的儿童进行尸检时采集的脾脏进行研究，结果显示，37%的病例中存在淋巴滤泡和浆细胞增生，其中只有少数病例的滤泡具有多层结构；19%的病例出现淋巴细胞耗竭。其余病例呈现出初级类型的小而无组织的淋巴滤泡，有些病例因其结节具有“上皮样模式”的“核心”而引人注目。高强度的嗜派洛宁反应在原发性支气管肺炎中占优势，但与肺和肺门-气管支气管淋巴结不同的是，在脾脏中，伴有或不伴有肺外炎症的原发性肺炎病例在反应的两个值组之间没有差异。免疫荧光显示，免疫球蛋白的三类物质按降序排列为：IgM、IgG和IgA。
