抑制3-甲基胆蒽诱导的细胞色素P-450酶活性的单克隆抗体。 - Suppr

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超能文献

Monoclonal antibodies that inhibit enzyme activity of 3-methylcholanthrene-induced cytochrome P-450.

作者信息

Park S S, Fujino T, West D, Guengerich F P, Gelboin H V

出版信息

Cancer Res. 1982 May;42(5):1798-808.

PMID:6175397

Abstract

摘要

相似文献

Monoclonal antibodies that inhibit enzyme activity of 3-methylcholanthrene-induced cytochrome P-450.抑制3-甲基胆蒽诱导的细胞色素P-450酶活性的单克隆抗体。

Cancer Res. 1982 May;42(5):1798-808.

Different patterns of benzo[a]pyrene metabolism of purified cytochromes P-450 from methylcholanthrene, beta-naphthoflavone and phenobarbital treated rats.来自经甲基胆蒽、β-萘黄酮和苯巴比妥处理的大鼠的纯化细胞色素P-450对苯并[a]芘的不同代谢模式。

Carcinogenesis. 1982;3(2):129-33. doi: 10.1093/carcin/3.2.129.

Effects of phenobarbital, 3-methylcholanthrene and beta-naphthoflavone pretreatment on mouse liver microsomal enzymes and on metabolite patterns of benzo[a]pyrene.苯巴比妥、3-甲基胆蒽和β-萘黄酮预处理对小鼠肝脏微粒体酶及苯并[a]芘代谢物模式的影响。

Biochem Pharmacol. 1981 Jun 1;30(11):1337-43. doi: 10.1016/0006-2952(81)90318-x.

Immunochemical study on the contributions of two molecular species of microsomal cytochrome P-450 to the metabolism of benzo(a)pyrene by rat liver microsomes.关于微粒体细胞色素P-450的两种分子形式对大鼠肝脏微粒体代谢苯并(a)芘贡献的免疫化学研究。

Cancer Res. 1983 Aug;43(8):3604-8.

Monoclonal antibodies to phenobarbital-induced rat liver cytochrome P-450.针对苯巴比妥诱导的大鼠肝脏细胞色素P-450的单克隆抗体。

Biochem Pharmacol. 1984 Jul 1;33(13):2071-81. doi: 10.1016/0006-2952(84)90576-8.

Comparison of cytochromes P-450 with high activity toward benzo[a]pyrene purified from liver microsomes of beta-naphthoflavone and 3-methylcholanthrene-pretreated rats.从经β-萘黄酮和3-甲基胆蒽预处理的大鼠肝脏微粒体中纯化得到的、对苯并[a]芘具有高活性的细胞色素P-450的比较。

Arch Biochem Biophys. 1982 Oct 15;218(2):472-7. doi: 10.1016/0003-9861(82)90369-1.

Bioactivation of 8-methoxypsoralen and irreversible inactivation of cytochrome P-450 in mouse liver microsomes: modification by monoclonal antibodies, inhibition of drug metabolism and distribution of covalent adducts.8-甲氧基补骨脂素在小鼠肝脏微粒体中的生物活化及细胞色素P-450的不可逆失活：单克隆抗体的修饰、药物代谢抑制及共价加合物的分布

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Purification and characterization of three forms of microsomal cytochrome P-450 in liver from 3-methylcholanthrene-treated guinea pigs.从经3-甲基胆蒽处理的豚鼠肝脏中纯化和鉴定三种形式的微粒体细胞色素P-450

Mol Pharmacol. 1983 Jan;23(1):258-64.

[Cytochrome P-450 isoforms in the liver of rats treated with phenobarbital, 3-methylcholanthrene and Aroclor 1254 studied by monoclonal antibodies].[用单克隆抗体研究经苯巴比妥、3-甲基胆蒽和多氯联苯混合物Aroclor 1254处理的大鼠肝脏中的细胞色素P-450同工酶]

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Regulation of cytochrome P450 in cultured human colonic cells.培养的人结肠细胞中细胞色素P450的调控

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A comprehensive investigation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) metabolism in the mouse using a multivariate data analysis approach.使用多变量数据分析方法对小鼠体内2-氨基-1-甲基-6-苯基咪唑并[4,5-b]吡啶（PhIP）代谢进行的全面研究。

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Mouse lung CYP1A1 catalyzes the metabolic activation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).小鼠肺细胞色素P450 1A1（CYP1A1）催化2-氨基-1-甲基-6-苯基咪唑并[4,5-b]吡啶（PhIP）的代谢活化。

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Retention of membrane proteins by the endoplasmic reticulum.内质网对膜蛋白的滞留

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