Cutropia de Guirao C
Acta Gastroenterol Latinoam. 1977 Dec;7(4):293-9.
The objective of the present investigation is the study and interpretation of the role played by the immunoglobulins, especially IgA, during acute diarrhea in children. IgA, IGG and IgM values in serum and IgA in intestinal secretions were studied in a group of children (between 3 months and 5 years of age) during diarrhea, convalescence and in normals. The method of simple radial immunodiffusion according to Mancini was employed. IgA is the immunoglobulin which suffers the greastest alteration in acute diarrhea. The precipitation halos (the average values), were lower during the diarrhea than in convalescence and in normals.
本研究的目的是研究和解释免疫球蛋白，尤其是IgA，在儿童急性腹泻期间所起的作用。对一组（年龄在3个月至5岁之间）儿童在腹泻期、恢复期及正常状态下的血清中IgA、IgG和IgM值以及肠道分泌物中的IgA值进行了研究。采用了根据曼奇尼法的简单放射免疫扩散法。IgA是在急性腹泻中变化最大的免疫球蛋白。沉淀环（平均值）在腹泻期低于恢复期及正常状态。
