Kalish S B, Kurtides E S, Semerdjian R A, Vagher P
South Med J. 1982 Apr;75(4):494-6. doi: 10.1097/00007611-198204000-00035.
We present a case in which an activated partial thromboplastin time (aPTT) inhibitor may have significantly contributed to prolonged bleeding in a patient and review five similar cases. The possibility of an aPTT inhibitor should be considered in the evaluation of patients with unexplained prolongation of PTT and PT. Such patients may develop significant bleeding even in the absence of other hematologic abnormalities.
我们报告了一例活化部分凝血活酶时间（aPTT）抑制剂可能显著导致患者出血时间延长的病例，并回顾了五例类似病例。在评估凝血酶原时间（PT）和活化部分凝血活酶时间（PTT）原因不明延长的患者时，应考虑存在aPTT抑制剂的可能性。即使没有其他血液学异常，这类患者也可能发生严重出血。
