Kusminsky R E, Tu K K, Brendemuehl J, Tiley E, Boland J P
Am Surg. 1982 Jul;48(7):359-62.
Widespread acceptance of Limulus Amoebocyte Lysate testing in clinical situations has been elusive. The results obtained in this series of 38 patients seem to support the contention that the amylase-endotoxin complex can be of value in detecting rapidly and with reasonable sensitivity the presence of pancreatic injury and gastrointestinal perforations. A corrected WBC count appears to add diagnostic possibilities to the technique. Despite the promising evidence detailed in this paper, further studies are required to establish the true sensitivity/specificity of the test. Its validity and utility could be assessed rapidly if traumatologists who routinely perform lavage would utilize this method and report their findings.
鲎试剂检测在临床环境中的广泛应用一直难以实现。在这38例患者系列中获得的结果似乎支持这样一种观点，即淀粉酶 - 内毒素复合物在快速且以合理的敏感性检测胰腺损伤和胃肠道穿孔的存在方面可能具有价值。校正后的白细胞计数似乎为该技术增加了诊断可能性。尽管本文详细阐述了有前景的证据，但仍需要进一步研究来确定该检测的真正敏感性/特异性。如果常规进行灌洗的创伤科医生使用这种方法并报告他们的发现，其有效性和实用性可以迅速得到评估。
