Mang W L, Hammer C
Laryngol Rhinol Otol (Stuttg). 1981 Jul;60(7):385-6.
Sera of patients with squamous cell carcinoma of the tonsil contain antibodies of IgG type, which seem to be directed against individual specific and group specific tumour cell surface antigen. Such antibodies which react with antigen on tumour cells of operation speciems also also mark cells from oral swabs, which are supposed to be of malignant origine. This suggestion is supported by the observation, that 3-6 months after the first positive findings recurrancy occurs. Therefore this method would be a simple, non invasive possibility for early detection of recurrancy in patient with tonsillar carcinoma and thus be of prognostic and diagnostic value.
扁桃体鳞状细胞癌患者的血清中含有IgG型抗体，这些抗体似乎针对个体特异性和群体特异性肿瘤细胞表面抗原。与手术标本肿瘤细胞上的抗原发生反应的此类抗体也能标记来自口腔拭子的细胞，这些细胞被认为起源于恶性肿瘤。首次发现阳性结果3至6个月后出现复发这一观察结果支持了这一推测。因此，该方法将是一种简单、非侵入性的早期检测扁桃体癌患者复发的方法，从而具有预后和诊断价值。
