系统性红斑狼疮中的抗体依赖性细胞毒性作用
Antibody-dependent cellular cytotoxicity in systemic lupus erythematosus.
作者信息
Láng I, Fekete B, Pálóczi K, Sonkoly I, Szegedi G, Török K, Gergely P, Petrányi G
出版信息
Acta Med Acad Sci Hung. 1977;34(4):259-65.
PMID:618057
Abstract
Antibody-dependent cellular cytotoxicity of peripheral blood mononuclear cells from fourty-six patients with systemic lupus erythematosus was found to be reduced in two independent test systems. The percentage decrease in cytotoxicity was similar in the tests with allogeneic and xenogeneic targets and it was related to the activity of systemic lupus erythematosus.
摘要
在两个独立的测试系统中发现，46例系统性红斑狼疮患者外周血单个核细胞的抗体依赖性细胞毒性降低。在针对同种异体和异种靶标的测试中，细胞毒性的降低百分比相似，且与系统性红斑狼疮的活动有关。
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