Geokas M C, Yalow R S, Straus E W, Gold E M
Ann Intern Med. 1982 Sep;97(3):389-407. doi: 10.7326/0003-4819-97-3-389.
The radioimmunoassay technique, first developed for the determination of hormones, has been applied to many substances of biologic interest by clinical and research laboratories around the world. It has had an enormous effect in medicine and biology as a diagnostic tool, a guide to therapy, and a probe for the fine structure of biologic systems. For instance, the assays of insulin, gastrin, secretin, prolactin, and certain tissue-specific enzymes have been invaluable in patient care. Further refinements of current methods, as well as the emergence of new immunoassay techniques, are expected to enhance precision, specificity, reliability, and convenience of the radioimmunoassay in both clinical and research laboratories.
放射免疫测定技术最初是为测定激素而开发的，现已被世界各地的临床和研究实验室应用于许多具有生物学意义的物质。作为一种诊断工具、治疗指南以及生物系统精细结构的探测手段，它在医学和生物学领域产生了巨大影响。例如，胰岛素、胃泌素、促胰液素、催乳素以及某些组织特异性酶的测定在患者护理中具有不可估量的价值。预计当前方法的进一步改进以及新免疫测定技术的出现，将提高放射免疫测定在临床和研究实验室中的精密度、特异性、可靠性和便利性。
