Voloshin N A, Iakhnitsa A G
Arkh Anat Gistol Embriol. 1982 May;82(5):83-9.
Morphological reactions of the thymus to penetration of foreign antigens into the organism should be further investigated. In the work presented, morphometric, histological and histochemical methods have been applied to study specific thymic reactions of the rat fetuses to antenatal antigenic stimulation. The antigenic stimulation of the fetuses results in an increased thymic function. The changes observed in it resemble, in general, an accidental involution. A specific feature of the fetal thymic reaction is an essential enlargement of the medullary substance volume and appearance of the thymic bodies (Hassall's bodies) that demonstrates an accelerated maturation of the thymus.
胸腺对外源抗原侵入机体的形态学反应有待进一步研究。在本研究中，采用形态计量学、组织学和组织化学方法，研究大鼠胎儿对产前抗原刺激的特异性胸腺反应。胎儿的抗原刺激导致胸腺功能增强。观察到的变化总体上类似于意外萎缩。胎儿胸腺反应的一个特点是髓质物质体积显著增大以及胸腺小体（哈氏小体）出现，这表明胸腺成熟加速。
