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[肝外胆管闭锁的葛西手术:治愈还是姑息治疗?]

[Kasai's operation for extrahepatic bile duct atresia: a cure or palliative treatment?].

作者信息

Blanchard H, Brochu P, Bensoussan A L, Montupet P

出版信息

Can J Surg. 1982 Sep;25(5):486-8.

PMID:6180817
Abstract

The only surgical treatment currently available for patients with extrahepatic biliary atresia is portoenterostomy or portocholecystostomy, the Kasai operation. Seventeen such patients were operated upon at the Hôpital Sainte-Justine; 11 had bile excretion. Eight are still alive 12 to 60 months after operation. They have good to fair bile excretion. Twelve of the 17 patients had infectious or hemorrhagic complications and hepatic deficiency is evident in 6 of the 8 living patients. The progressive deterioration of liver function in the majority of the patients still alive raises the question of whether the Kasai procedure should be considered a curative or only a palliative procedure.

摘要

目前,肝外胆管闭锁患者唯一可用的手术治疗方法是肝门空肠吻合术或肝门胆囊吻合术,即葛西手术。圣朱斯汀医院对17名此类患者进行了手术;其中11名有胆汁排出。8名患者术后12至60个月仍然存活。他们的胆汁排出情况良好或尚可。17名患者中有12名出现感染或出血并发症,8名存活患者中有6名存在肝功能不足。大多数仍存活患者的肝功能进行性恶化,这引发了一个问题,即葛西手术应被视为一种治愈性手术还是仅仅是一种姑息性手术。

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