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大鼠新纹状体神经元的高尔基染色研究:光学显微镜分析

A Golgi study of rat neostriatal neurons: light microscopic analysis.

作者信息

Chang H T, Wilson C J, Kitai S T

出版信息

J Comp Neurol. 1982 Jun 20;208(2):107-26. doi: 10.1002/cne.902080202.

DOI:10.1002/cne.902080202
PMID:6181102
Abstract

At least two types of large neurons (somatic cross-sectional areas, SA greater than 300 microns2) and five-types of medium neurons (SA between 100 and 300 microns2) were distinguished in Golgi preparations of the adult rat neostriatum. Type I large cells had aspinous somata with long, radiating, sparsely spined dendrites which were sometimes varicose distally, whereas type II large cells had spines on both somatic and dendritic surfaces. Type I medium cells had aspinous somata and proximal dendrites, but their distal dendrites were densely covered with spines. Type II medium cells had somatic spines, and their radiating dendrites were sparsely spined. Other medium cells had no somatic spines: Type III cells had poorly branched and sparsely spined dendrites. Type IV cells had profusely branched, sparsely spined dendrites. Type V cells had radiating and varicose dendrites which could also be sparsely spined. Several small neurons (SA mostly less than 100 microns2) were also found in the rat neostriatum: Some had aspinous soma with sparsely spined dendrites; others had somatic spines. Except for the type II large cells, intrinsic axon collaterals were observed for every type of neuron, indicating that they all had local integrating functions.

摘要

在成年大鼠新纹状体的高尔基染色标本中,区分出了至少两种类型的大神经元(体细胞横截面积,SA大于300平方微米)和五种类型的中型神经元(SA在100至300平方微米之间)。I型大细胞的胞体无棘,有长的、呈放射状的、稀疏有棘的树突,这些树突有时在远端呈曲张状,而II型大细胞在胞体和树突表面都有棘。I型中型细胞的胞体和近端树突无棘,但其远端树突密集分布有棘。II型中型细胞有胞体棘,其放射状树突稀疏有棘。其他中型细胞无胞体棘:III型细胞的树突分支少且棘稀疏。IV型细胞的树突分支多且棘稀疏。V型细胞有放射状且曲张的树突,也可能稀疏有棘。在大鼠新纹状体中还发现了一些小神经元(SA大多小于100平方微米):一些小神经元的胞体无棘,树突稀疏有棘;另一些有胞体棘。除了II型大细胞外,每种类型的神经元都观察到了内在轴突侧支,这表明它们都具有局部整合功能。

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