Cowie R A, Hitchcock E R
Acta Neurochir (Wien). 1982;64(1-2):39-50. doi: 10.1007/BF01405617.
The operation of antero-lateral cordotomy was carried out on 56 patients with intractable pain between 1968 and 1978. The follow-up of these patients was continued for at least three years or until death to determine the late success of this procedure. Of the 33 patients who underwent surgery for malignant pain 95% of survivors had effective relief on discharge from hospital, the success rate falling to 73% at six months, and 55% at one year of follow-up. The operation was judged successful for patients with malignant disease because of short life expectancy. Thirteen patients had chronic pain from non-malignant conditions, and 85% obtained initial relief, the success rate falling to 35% at one year, and 20% at three years of follow-up. Two patients died from respiratory failure, giving an operative mortality of 3.5%. The results and complications of open cordotomy are compared with those of the percutaneous method, and the role of this procedure discussed in relation to alternative stimulatory analgesic procedures.
1968年至1978年间,对56例顽固性疼痛患者实施了脊髓前外侧切断术。对这些患者进行了至少三年的随访或直至死亡,以确定该手术的远期效果。在33例因恶性疼痛接受手术的患者中,95%的幸存者在出院时疼痛得到有效缓解,六个月时成功率降至73%,随访一年时为55%。由于恶性疾病患者预期寿命较短,该手术对他们被判定为成功。13例患者患有非恶性疾病引起的慢性疼痛,85%的患者最初疼痛得到缓解,随访一年时成功率降至35%,三年时为20%。两名患者死于呼吸衰竭,手术死亡率为3.5%。将开放性脊髓切断术的结果和并发症与经皮脊髓切断术的结果和并发症进行了比较,并讨论了该手术相对于其他刺激性镇痛方法的作用。