Bennett F C, Robinson N M, Sells C J
Am J Dis Child. 1982 Oct;136(10):888-91. doi: 10.1001/archpedi.1982.03970460018003.
Mean mental and motor developmental test scores (Bayley scales) at 4, 12, and 24 months of age were determined for 161 graduates of a neonatal intensive care unit during the period 1977 through 1979. Analysis of variance for our data showed significant effects of hyaline membrane disease (HMD) on mental and motor development at 4 months, but disappearance of these effects at 12 and 24 months of age. Conversely, birth weight was not significantly related to developmental performance at 4 months, but was strongly related to both mental and motor performance at 12 and 24 months of age. Gestational age was significantly related to mental performance at 24 months of age. No relationship was found between HMD and major CNS handicapping conditions; both birth weight and gestational age were highly related to the occurrence of neurologic handicaps. Of the three variables assessed, birth weight was the best predictor of neurodevelopmental outcome.
1977年至1979年期间，对161名新生儿重症监护病房的毕业生进行了4个月、12个月和24个月大时的平均智力和运动发育测试评分（贝利量表）测定。对我们的数据进行方差分析显示，透明膜病（HMD）在4个月时对智力和运动发育有显著影响，但在12个月和24个月大时这些影响消失。相反，出生体重在4个月时与发育表现无显著相关性，但在12个月和24个月大时与智力和运动表现密切相关。孕龄在24个月时与智力表现显著相关。未发现HMD与主要中枢神经系统残疾状况之间存在关联；出生体重和孕龄均与神经残疾的发生高度相关。在评估的三个变量中，出生体重是神经发育结局的最佳预测指标。
