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胃底腺癌的胃切除术选择

Selection of gastrectomy for adenocarcinomas arising in the gastric fundus.

作者信息

Papachristou D N, Fortner J G

出版信息

J Surg Oncol. 1982 Nov;21(3):165-9. doi: 10.1002/jso.2930210307.

Abstract

A retrospective study involving 174 patients with adenocarcinoma of the gastric fundus treated with proximal subtotal (PS), extended proximal subtotal (EPS), total (T), and extended total (ET) gastrectomy showed that 1)there were no statistically significant differences in operative mortality between the four gastrectomy types; 2)ET was associated with a significantly lower incidence of local recurrence than T (P less than 0.05) and PS (P less than 0.001); 3)ET resulted in a significantly higher survival rate than PS or T (P less than 0.01) when the three procedures were applied in patients who had TNM stage I and II tumors; 4)patients with stage III and IV tumors did poorly regardless of gastrectomy type. The study implies that intraoperative tumor staging might identify stage I and II patients who benefit the most from radical surgery and those with stage III and IV tumors who should receive palliative surgery.

摘要

一项回顾性研究涉及174例胃底腺癌患者,这些患者接受了近端次全切除术(PS)、扩大近端次全切除术(EPS)、全胃切除术(T)和扩大全胃切除术(ET)。结果显示:1)四种胃切除术类型之间的手术死亡率无统计学显著差异;2)与全胃切除术(T)(P<0.05)和近端次全切除术(PS)(P<0.001)相比,扩大全胃切除术(ET)的局部复发率显著更低;3)当对TNM分期为I期和II期肿瘤的患者应用这三种手术时,扩大全胃切除术(ET)的生存率显著高于近端次全切除术(PS)或全胃切除术(T)(P<0.01);4)无论胃切除术类型如何,III期和IV期肿瘤患者的预后都很差。该研究表明,术中肿瘤分期可能有助于识别最能从根治性手术中获益的I期和II期患者,以及应接受姑息性手术的III期和IV期肿瘤患者。

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