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关于安托抗原与抗体的观察报告。

Observations on the Anton antigen and antibody.

作者信息

Poole J, Giles C M

出版信息

Vox Sang. 1982;43(4):220-2. doi: 10.1111/j.1423-0410.1982.tb00015.x.

DOI:10.1111/j.1423-0410.1982.tb00015.x
PMID:6182694
Abstract

Five antisera with Anton specificity were studied serologically. The determinant is not sensitive to treatment by proteolytic enzymes (notably trypsin) and is present on cells of the recessive type of Lu(a-b-) phenotype. The Anton 'para-Lutheran' antigen/antibody therefore seems to be associated with the Lutheran blood group system only by means of cells of the dominant type of the Lu(a-b-) phenotype which is controlled by In(Lu), a gene independent of the Lutheran locus.

摘要

对五份具有安托恩特异性的抗血清进行了血清学研究。该决定簇对蛋白水解酶(尤其是胰蛋白酶)处理不敏感,且存在于隐性类型的Lu(a-b-)表型细胞上。因此,安托恩“类路德”抗原/抗体似乎仅通过由In(Lu)控制的显性类型的Lu(a-b-)表型细胞与路德血型系统相关联,In(Lu)是一个独立于路德基因座的基因。

相似文献

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Preliminary serological studies of 4 monoclonal antibody samples with "Lutheran" specificities.对4个具有“路德氏”特异性的单克隆抗体样本进行的初步血清学研究。
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