Komolova G S, Troitskaia E N, Egorov I A, Tigranian R A
Kosm Biol Aviakosm Med. 1982 Sep-Oct;16(5):66-9.
Changes in nucleic acid metabolism of the spleen and liver of rats flown for 18.5 days on Cosmos-112 were investigated. Postflight changes in the liver RNA synthesis after an additional stress effect (immobilization) in the flown rats were expressed to a lesser degree than in the controls. The DNA synthesis remained essentially at the preflight level. The tissue content of nucleic acids suggests that postflight the dystrophic changes induced by the additional stress effect increased. It is very likely that an exposure to space flight effects contributes to the depletion of compensatory mechanisms maintaining the normal level of metabolic processes.
对在“宇宙-112”号上飞行18.5天的大鼠脾脏和肝脏的核酸代谢变化进行了研究。飞行后的大鼠在受到额外应激效应（固定）后，肝脏RNA合成的飞行后变化程度低于对照组。DNA合成基本保持在飞行前水平。核酸的组织含量表明，飞行后由额外应激效应引起的营养不良性变化增加。很可能暴露于太空飞行效应会导致维持代谢过程正常水平的代偿机制耗竭。
