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两个紧密连锁的基因座和一个明显独立的基因座编码牛淋巴细胞抗原。

Two closely linked loci and one apparently independent locus code for bovine lymphocyte antigens.

作者信息

Stear M J, Newman M J, Nicholas F W

出版信息

Tissue Antigens. 1982 Oct;20(4):289-99. doi: 10.1111/j.1399-0039.1982.tb00359.x.

DOI:10.1111/j.1399-0039.1982.tb00359.x
PMID:6183787
Abstract

Twenty different antigens have been detected on bovine lymphocytes. Family studies suggested that 19 of the antigens were under the control of two closely-linked loci. The remaining antigen was apparently coded for by an independent locus. The distribution of the antigens in the population also suggested that three loci control the expression of lymphocyte antigens. A co-capping study on two antigens which were inherited together on one haplotype showed that these antigens were expressed on different molecules on the lymphocyte membrane, providing further evidence for the existence of two linked loci.

摘要

已在牛淋巴细胞上检测到20种不同的抗原。家系研究表明，其中19种抗原受两个紧密连锁的基因座控制。其余的抗原显然由一个独立的基因座编码。这些抗原在群体中的分布也表明，三个基因座控制淋巴细胞抗原的表达。对在一个单倍型上共同遗传的两种抗原进行的共帽研究表明，这些抗原在淋巴细胞膜上的不同分子上表达，为两个连锁基因座的存在提供了进一步的证据。

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